Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the gamma-Aminobutyric Acid Type A Receptor (GABA(A)R) alpha 6 Subtype with Improved Metabolic Stability and Enhanced Bioavailability

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Naziv:	Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the gamma-Aminobutyric Acid Type A Receptor (GABA(A)R) alpha 6 Subtype with Improved Metabolic Stability and Enhanced Bioavailability
Autori:	Knutson, Daniel; Kodali, Revathi; Divović, Branka ; Treven, Marco; Stephen, Michael; Zahn, Nicolas; Dobričić, Vladimir ; Huber, Alec; Meirelles, Matheus; Verma, Ranjit; Wimmer, Laurin; Witzigmann, Christopher; Arnold, Leggy; Chiou, Lih-Chu; Ernst, Margot; Mihovilović, Marko D.; Savić, Miroslav ; Sieghart, Werner; Cook, James M.;
Godina:	2018
Publikacija:	Journal of Medicinal Chemistry
ISSN:	0022-2623 Journal of Medicinal Chemistry Pretraži identifikator
Izdavač:	Amer Chemical Soc, Washington
Tip rezultata:	Naučni članak
Kolacija:	vol. 61 br. 6 str. 2422-2446
DOI:	10.1021/acs.jmedchem.7b01664
WoS-ID:	000428356600015
Scopus-ID:	2-s2.0-85044203204
PMID:	29481759
URI:	https://enauka.gov.rs/handle/123456789/525622 https://farfar.pharmacy.bg.ac.rs/handle/123456789/3147
Projekat:	National Institutes of Health (NIH) - R01 NS076517
M-kategorija:	21a+M21a+ - Vodeći međunarodni časopis kategorije M21a+

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