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New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High Oral Plasma and Brain Exposures, and Produces Antiseizure Efficacy in Mice, and Antiepileptogenic Activity in Neural Networks in Brain Slices from a Patient with Mesial Temporal Lobe Epilepsy
| Naziv: | New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High Oral Plasma and Brain Exposures, and Produces Antiseizure Efficacy in Mice, and Antiepileptogenic Activity in Neural Networks in Brain Slices from a Patient with Mesial Temporal Lobe Epilepsy | Autori: | Sharmin, Dishary; Divović, Branka   ; Ping, Xingjie; Cerne, Rok; Smith, Jodi L.; Rezvanian, Sepideh; Mondal, Prithu; Michelle, Meyer Jean; Kiley, Molly E.; Arnold, Leggy A.; |
Godina: | 2023 | Publikacija: | ACS Chemical Neuroscience | ISSN: | 1948-7193 ACS Chemical Neuroscience Pretraži identifikator |
Izdavač: | American Chemical Society | Tip rezultata: | Naučni članak | DOI: | 10.1021/acschemneuro.3c00555 | WoS-ID: | 001158535100001 | Scopus-ID: | 2-s2.0-85182005653 | PMID: | 38175916 | URI: | https://enauka.gov.rs/handle/123456789/883159 https://farfar.pharmacy.bg.ac.rs/handle/123456789/5505 |
Projekat: | Henry and Nelly Pence Foundation Trust AA029023, DA-043204, DA054177, NS-076517 Milwaukee Institute of Drug Discovery UW-Milwaukee Shimadzu Laboratory for Advanced and Applied Analytical Chemistry University of Wisconsin-Milwaukee Research Foundation |
Izvor metapodataka: | (Preuzeto iz Nasi u WoS) | M-kategorija: | 21M21 - Vodeći međunarodni časopis kategorije M21 |
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